This study explores how muscle force, pressure, and strain interact during active skeletal muscle contractions using in silico modeling. While pressure has often been used as a proxy for muscle force, the authors demonstrate its limitations due to boundary pressure relaxation. Instead, they identify strong correlations between force and principal, shear, and volumetric strains. The...
This study evaluates shape memory polymer (SMP) scaffolds designed for patient‑specific endovascular treatment of intracranial aneurysms. Using in‑vitro experiments, the authors characterize how scaffold formulation, porosity, and infill architecture influence key translational metrics, including glass transition behavior, catheter‑compatible compressibility, pulsatile compaction resistance, and shape recovery performance. The results show that SMP scaffolds can be tuned...
Congratulations to Tanner for placing first in The University of Oklahoma's 2025 Three Minute Thesis competition, explaining his research on "Shape Memory Polymer Scaffolds with Tunable Architecture for the Endovascular Treatment of Cerebral Aneurysms." Tanner will represent the University of Oklahoma in the 82nd Midwestern Association of Graduate Schools regional Three Minute Thesis competition in...
This study, titled ' State-space formulations to understand the nonlinear viscoelastic mechanical behavior of tricuspid valve chordae tendineae," investigates the complex mechanical behavior of tricuspid valve chordae tendineae using state-space representations of nonlinear viscoelastic models. By capturing time-dependent and nonlinear stress-strain relationships, the authors provide a framework for simulating chordae dynamics under physiological loading. This...
Their study, titled " ValveFit : An analysis-suitable B-spline-based surface fitting framework for patient-specific modeling of tricuspid valves," introduces ValveFit, a computational framework designed to generate smooth, analysis-ready B-spline surfaces for modeling tricuspid heart valves. The method enables accurate, patient-specific reconstructions from imaging data, improving the fidelity of biomechanical simulations used in clinical assessments. By...
Congratulations to Dr. Lee and Collaborators from Lehigh University (Dr. Jihong Wang and Dr. Yue Yu) and University of Arkansas (Dr. William Richardson) on their recent conference paper at the 2025 IEEE International Conference on Image Processing (ICIP)! Their paper, “ A Physics-Guided Smoothing Method For Material Modeling With Digital Image Correlation (DIC) Measurements,” introduces...
On Friday, August 15, Tiffany and Shubi presented their research at the 2025 MSRIP Conference hosted at UC Riverside. This full-day event brought together undergraduate researchers, graduate students, and faculty to share projects and exchange ideas. Tiffany presented her poster, “Tricuspid Valve Simulation Applied Through the Right Heart Simulator,” highlighting how simulation-based approaches can improve...
We are proud to share that Tiffany was awarded the Maria Franco-Gallardo Excellence Award at the 2025 MSRIP Conference, recognizing her poster as the best in the conference. Her project, “Tricuspid Valve Simulation Applied Through the Right Heart Simulator,” stood out for its innovation, clarity, and potential impact on understanding cardiac valve function. The award...
We are proud to celebrate Sofia (right, front row), Aidan (right, back row), and Oliver (left, back row) for successfully completing their five-week STRIDE internship with the Biomechanics and Biomaterials Design Laboratory (BBDL) at UCR. During the program, they conducted hands-on research on critical topics including heart valve mechanics, mesh independence studies, and histological analysis...
Congratulations to Tanner and Collaborators from Purdue (Dr. Hyowon Lee) and Indiana University School of Medicine (Dr. Bradley Bohnstedt) on their recent publication in Annals of Biomedical Engineering! Their paper, “Towards the Intravascular Delivery of 3D-printed Leached SMP for Endovascular Treatment of Intracranial Aneurysm,” introduces a new approach to treating aneurysms using 3D-printed shape memory...
Congratulations to Maedeh, Zach, Shubi, and Yasmin on their recent publication in Frontiers of Bioengineering and Biotechnology. Their paper "Evaluation of the effects of clearing agents, fixation, and process durations on cardiovascular tissue imaging with second harmonic generation and multi-photon modalities," explores how sample preparation methods influence advanced imaging outcomes in cardiovascular tissues. By systematically...
Congratulations to Dr. Colton Ross and UG student Mr. Michael Burkhart in collaboration with Dr. Li-Wei Liu at National Taiwan University on the recent publication in Applied Mathematical Modeling! Their paper, “State-space formulations to understand the nonlinear mechanical behavior of the tricuspid valve chordae tendineae,” introduces a novel state-space modeling framework to better characterize chordae...
Shubi and Yasmin presented their research at UCR’s Undergraduate Research and Creative Activities Symposium, representing the BBDL. Their project, “Evaluation of the Effects of Clearing Agents, Fixation, and Process Durations on Cardiovascular Tissue Imaging,” explored how different tissue preparation techniques impact autofluorescence and second harmonic generation signals during multi-photon imaging. Their findings support the use...
The team including our lab members Phiphi and Yasmin developed the Biomechanical Alignment eXosystem, a wearable device designed to help improve poor posture via auditorial and physical reminders. They successfully won fourth place among over 40 teams at the school's only make-a-thon competition!
The paper Heterogeneous peridynamic neural operators: Discover biotissue constitutive law and microstructure from digital image correlation measurements introduces the Heterogeneous Peridynamic Neural Operator (HeteroPNO) approach for data-driven constitutive modeling of heterogeneous anisotropic materials based on digital image correlation (DIC) data. The two-phase learning approach utilizes an nonlocal constitutive law and spatially varying fiber orientation fields...
Phiphi presented her research at the 2025 Koret UC LEADS Symposium hosted at UCLA. Representing the BBDL, she shared her work with peers and faculty from across the UC system. Her presentation reflected strong scientific curiosity and growing expertise in the field. We’re excited to see her continued growth and contributions.
The BBDL welcomes Ashley Taepadee to the lab. Ashley will be starting her PhD this year with a focus on aneurysm treatments. Her past research experience and passion will hopefully serve her well in our lab. We are excited to see the contributions she'll make as she begins this next chapter.
Congratulations to Dr. Das and Tanner on their recent publication in Journal of the Mechanical Behavior of Biomedical Materials. Their article, " Design of Thermally Programmable 3D SMP-Based Embolic Devices for Endovascular Aneurysm Treatment," presents an innovative approach to aneurysm treatment using thermally responsive shape memory polymers. This work underscores the potential of programmable materials...
The study used computational fluid dynamics to evaluate the hemodynamic and heat transfer effects of shape-memory polymer foam (SMPf) devices in six patient-specific aneurysm geometries. The SMPf device, modeled as a porous medium, significantly reduces intra-aneurysmal blood flow and demonstrates effective thermal behavior under worst-case conditions. The findings offered a validated, practical framework for optimizing...
Dr. Ankush Aggarwal from the University of Glasgow visited UC Riverside as part of the 2024–2025 Bioengineering Colloquium Series. He delivered an insightful seminar titled “Improved Cardiovascular Healthcare via Computational Tissue Biomechanics: Applications to Vasculature.” In his talk, Dr. Aggarwal discussed the crucial role of soft tissue mechanics in cardiovascular health and shared recent advances...
